Monday, November 24, 2014

Motivation Monday

Where we are headed into a holiday week with lots of tempting treats, what better motivation than to share the impact of Dr. Bruce Spiegelman's research on the link between obesity and cancer, which determined why obesity is a risk factor in 10-15% of human cancers. Dr. Spiegelman's research, supported by the Barr program in 2005, demonstrated that obesity causes many body-wide alterations in metabolism, hormone levels, and inflammation, and that these abnormalities may affect the development and progression of cancers. Determining the link between obesity and these cancers could be instrumental to inhibiting cancer development in both obese and non-obese people, leading to the potential for major breakthroughs in the development of new ways to treat and prevent cancer.

Something to think about when reaching for that second helping of mashed potatoes...or rather, to give you motivation to go run them off after!



Oh and since we're talking second helpings of mashed potatoes - why not a second helping of motivation to go with it?


Wherever you find yourself running (and eating mashed potatoes) this week, I wish you and your families a blessed and happy Thanksgiving holiday. We have so much to be thankful for, and I am particularly thankful for my health and all of you!


Monday, November 17, 2014

New and Improved Monday Motivation

Happy Monday everyone!  This past week we had our first DFMC team meeting (a more complete recap forthcoming...it's been a busy week!) and it inspired me to reformat my Monday Motivation. Since the BIGGEST motivation is knowing that I am helping my team to raise over $5.3 billion dollars to fund cutting edge cancer research, I am going to start including some of the impact statements that give a sense for the truly life changing and saving research being done through the Barr Program, which receives 100% of the funds raised by the DFMC.

For example, the 2008 Barr research project of Loren Walensky, MD, PhD.  Dr. Walensky's project 
focused on the development of new therapies with the potential to reactivate the “executioner” function of cancer cells and prevent their uncontrollable growth.

All living cells contain “executioner proteins” that help control the growth of normal cells. 
Cancer cells find a way to prevent activation of these proteins, enabling them to replicate 
uncontrollably. Dr. Walensky generated novel compounds that bind to these proteins in cancer cells, reactivating their “executioner” function and triggering cell death. By integrating chemistry, biology and cancer medicine, this work has the potential to create groundbreaking new therapies for multiple types of cancer, many of which no longer respond to conventional therapies.

And NONE of that research - or that which has been done in the other amazing projects you will learn about each week - could have happened without the generous gifts from donors like you!

I am sure Dr. Walensky and so many other talented and dedicated researchers have had days where they were unsure whether their hard work would make a difference. But they push on undeterred, keeping the ultimate goal and finish line (a world without cancer) on the horizon, and their work has had tremendous and far reaching impact. Could you imagine what would have happened if they just gave up when it got hard?  Not an option.  So yes, while I will certainly have days where I am unsure whether I can raise $10,000 and run 26.2 miles, seeing the true impact this challenge makes is all the motivation I need.  




Tuesday, October 14, 2014

Half Marathon Eve

'Twas the night before the BAA Half and all through the house, this runner was nervous and chatting the ear off her spouse. Her clothes and supplies were all laid out with care, in hopes to avoid forgetting crucial items at 5:00am when coming downstairs.  And now she is headed to nestle snug in her bed, so visions of a BAA medal can dance in her head.  Merry half running to all and to all a good night!


Thursday, October 2, 2014

Lessons Learned From Achilles

In Greek mythology it is said that Achilles' mother, Thetis, dipped him in the river Styx as a child thus making him invincible, with the exception of the back of his heel by which she lowered him into the water. Guided by Apollo, Paris (in retribution for Achilles victories on the battlefield) aimed a poisoned arrow for Achilles' heel and killed him. Despite Achilles' having survived countless conflicts it was this one tiny vulnerable spot which bought down the mighty warrior. Hence we use the term Achilles Heel when referencing vulnerabilities - "my Achilles Heel is chocolate," for example. And anatomically, the tendon that connects our calf muscle to our heel bone bears Achilles' name.

Runners are not so different from Achilles. We train hard, we play hard, and we like to think we are invincible - though we are far from it. We all have our vulnerabilities and often it is the tiniest, and least expected, thing which can bring us down. I learned that lesson the hard way as of late thanks to my - you guessed it - Achilles tendon.

I was towards the end of my eleven mile long run two weekends ago when suddenly I felt a slight pain along the "spine" of my left Achilles tendon. Having never felt pain while running (beside the standard and expected pang of tired legs or the mental pain of knowing how many miles remain), I attempted to run it off. I made it through the last few miles but it was not easy. Returning home I took some advil, iced the area, and made the mistake of googling "runner achilles pain." Turns out Achilles pain and injuries are one of the top three runner ailments and while descriptions and diagnoses varied from article to article, the common takeaway was that you should stop running immediately if you experience Achilles pain.

Ummm, so you mean running that last three miles uphill wasn't a smart idea?

Ooops.

None-the-less, the pain disappeared as soon as I stopped running and I didn't feel even a hint of pain while walking the rest of that day, or on my Sunday rest day. Figuring this was a sign that the pain had been a mere irritation versus an injury, I embarked on my five mile Monday run with baited breath. The first three miles felt great and it seemed I may be in the clear. After pausing at a stoplight and starting up again, my hopes were dashed. There was the pain again - at first a slight whisper before quickly intensifying into a throbbing shout. And while I desperately wanted to pretend I could run it off, I knew better than to force it. Slowing to a walk, I gingerly made my way through the last two miles back to my office, twice attempting to run again before returning to a screeching halt due to the immediate pain.

Knowing I will be marathon training through Boston's brutal winter, I have been envisioning all the things that might bring me down in the months to come while attempting to strategize preventative solutions. Black Ice (sneaker treads). The flu (got my shot!). Two cats snuggling on my chest and making it hard to get up at 6:00am on a Saturday (yeah...I've got nothing for this one yet). But a little pain in the back of my heel? COME ON.

I took the next few days off.

Which was hard.

No, really...stop laughing...it was actually hard to rest!

Because despite the amount of times I may grumble about it, I truly and honestly love running. It clears my head, revs my energy, and floods me with those oh-so-wonderful happy endorphins. No happy endorphins = Cranky sluggish Erin.

Finally after a week of rest and some new sneakers, I headed back out on the Charles last week and since then, have logged some of my best runs yet.  Pain free.  Go figure.

Sometimes what seems like a setback is really just life forcing you to stop, take a breath, and prepare to surge forward.You have to look at the bigger picture and not just the moment at hand. Did I feel frustrated that I lost miles and training time as my first half-marathon quickly approaches next weekend? Yes. But did I learn a valuable lesson about taking care of myself and preventing an injury that could have sidelined me much longer or even permanently? Also yes.

I have been dwelling upon this during the ample time my enjoyable atrocious commute offers me. Historically, I would have just ignored the pain and kept running. And historically, that would have led to a severe injury forcing me to take off much, much more time from training, and which would eventually lead me to abandon running all together for a year. Or five. Oh yeah, I suppose I should briefly mention that time in L.A. when I basically broke my ankle mid-hike but insisted on hiking down the mountain, and then refused to seek medical attention due to my stubborn nature and lack of health insurance at the time. Bad decision making at its finest. But we live and we learn, or so they say - yes?

And yet, so often we really don't learn. It took me another run before I listened to that little voice in my head telling me to stop and take care of the pain. And honestly, had I not been scared by all those articles mentioning chronic achilles injuries that could prevent me from training for or running the marathon, I probably would have kept going. Despite having learned my lesson previously (and painfully). It is just human nature and symptomatic of the age we live in. We push things until they break. We never slow down. We are always flying forward at a million miles per hour until some thing, person, or event literally forces us to stop.

As I learn more about Dana-Farber's life saving and changing research, I am reminded even further of this. So often we discuss how to treat cancer - but a big part of it is prevention as well.  Taking care of yourself is the biggest way you can prevent cancer and other diseases from affecting you in your lifetime - and yet, despite knowing this, so many of us don't.We do not eat the way we should, or get enough rest. We do not see our doctors regularly or find ways to reduce the ever compounding stress in our lives. The list goes on and on. But it is crucial that we take the time to stop take care of ourselves, before something else forces us to.

None of us are invincible - that is the stuff of myths.  But by investing in your health and well being, you might just come as close to it as you can.